TY  - JOUR
T1  - Metabolite profiling, total polyphenolic contents and in vitro antioxidant properties of Sidaguri (Sida retusa L.) ‎
A1  - Ema Ratna Sari
A1  - Netty Suhatri
A1  - Friardi Ismed
A1  - Deddi Prima Putra
JF  - Journal of Advanced Pharmacy Education and Research
JO  - J Adv Pharm Educ Res
SN  - 2249-3379
Y1  - 2023
VL  - 13
IS  - 4
DO  - 10.51847/KMptNAVVX3
SP  - 109
EP  - 113
N2  - Sida retusa L. is a plant belonging to the Malvaceae family native to the tropical and subtropical plains grossing abundantly in Indonesia. Traditionally this plant is used for arthritis, asthma, cough, flatulence, colic, burning sensation, hemorrhoids, intermittent fever, and general debility. This study evaluates the chemical content in metabolite profiling, total polyphenolic contents, and in vitro antioxidant activity from Sida retusa L. leaves extract from West Sumatra, Indonesia. Metabolite profiling determination of Sida retusa L. extract using LC-MS/MS method, total phenolic and flavonoid contents, and antioxidant activity was determined by spectrophotometry. The results of the chromatogram interpretation revealed five main components of Sida retusa L. from West Sumatra were epoxypheophorbide A, scortechinone X, stigmastane-3β,5α,6β-triol, shidasterone B, and linolenic acid. Total phenolic and flavonoid contents from Sida retusa L. were 31.848 mg GAE/g and 12.242 mg QE/g). Sida retusa L. from West Sumatra had an antioxidant activity with IC50 value 468,137 ± 13,319 µg/mL. Sida retusa L. contains various potential secondary metabolites and sources of polyphenols and antioxidants and is a promising source of Indonesian natural ingredients‎.
UR  - https://japer.in/article/metabolite-profiling-total-polyphenolic-contents-and-in-vitro-antioxidant-properties-of-sidaguri-s-fl97bwqb5ladana
ER  -