TY  - JOUR
T1  - Investigation of the effectiveness of silver-containing drugs for the treatment of tuberculosis in the respiratory system‎
A1  - Leila Nurgamidovna Zairkhanova
A1  - Anna Sergeevna Eremina
A1  - Rasul Ruslanovich Burkhanov
A1  - Mata Magomedovna Bersanova
A1  - Susanna Zaurkanovna Agerzhanokova
A1  - Fatima Almanovna Muskhadzhieva
A1  - Asyat Isaevna Ataeva
A1  - Viktor Viktorovich Esyunin
JF  - Journal of Advanced Pharmacy Education and Research
JO  - J Adv Pharm Educ Res
SN  - 2249-3379
Y1  - 2024
VL  - 14
IS  - 3
DO  - 10.51847/zhfsdGkmQi
SP  - 31
EP  - 35
N2  - Tuberculosis lesion of the upper respiratory tract in most cases is a secondary disease and develops as a result of the introduction of a specific pathogen in patients suffering from pulmonary tuberculosis. Against the background of the deterioration of the general epidemiological situation of tuberculosis, its course has changed in the direction of aggravation of the process and an increase in diseases of extrapulmonary tuberculosis. It is known that silver nanoparticles restore the sensitivity of drug-resistant strains of tuberculosis microbacteria to chemotherapy drugs, and their growth is suppressed. The purpose of the study is to evaluate the effectiveness of the use of silver—containing drugs for the treatment of patients with tuberculosis of the upper respiratory tract. As a result of the study, it was found that silver nanoparticles demonstrate anti-tuberculosis activity. At the same time, the dose-dependent nature of the suppressive activity of nanoparticles was established. Argitos at a concentration of 3.3% showed higher therapeutic activity in the treatment of laryngeal tuberculosis compared with standard anti-tuberculosis drugs.
UR  - https://japer.in/article/investigation-of-the-effectiveness-of-silver-containing-drugs-for-the-treatment-of-tuberculosis-in-t-i9qcuvnbonxfupc
ER  -