TY  - JOUR
T1  - Correlation of serum interleukin-6 level and pneumonia severity index score in patient with community-acquired pneumonia
A1  - Resti Yudhawati
A1  - Evi Yuniawati
JF  - Journal of Advanced Pharmacy Education and Research
JO  - J Adv Pharm Educ Res
SN  - 2249-3379
Y1  - 2021
VL  - 11
IS  - 3
DO  - 10.51847/9Vb1tFdXHU
SP  - 58
EP  - 62
N2  - Biomarkers of pro-inflammatory cytokines have been widely evaluated for their efficacy in the assessment of disease severity. The pleiotropic functions of Interleukin-6 (IL-6) allow it to induce the inflammatory responses acute phase. This study aimed to evaluate the correlation between PSI scores in patients with CAP and IL-6 levels. The study was a cross-sectional study. 26 pneumonia patients who met the inclusion and exclusion criteria were included in this study. IL-6 levels and PSI scores were calculated on the first day of patients treated. 

The mean±SD of PSI scores and IL-6 levels were 161.860±75.0042 and 88.58±25.511 respectively. The cut off point of IL-6 was 184.182 with 28% AUC (95% confidence interval of 10,4% – 45,6%) with p-value > 0.05. There was a significant correlation between the PSI score and interleukin-6 level with a strong positive correlation r = 0.673 (p-value 
UR  - https://japer.in/article/correlation-of-serum-interleukin-6-level-and-pneumonia-severity-index-score-in-patient-with-communit-wjvilndiunarjrf
ER  -