%0 Journal Article
%T Clinical pharmacist intervention in Appendectomy - Dexmedetomidine as an adjunct therapy
%A Bushra Abdel-Hadi
%A Sami Raid Abdel-Fattah
%J Journal of Advanced Pharmacy Education and Research
%@ 2249-3379
%D 2022
%V 12
%N 2
%R 10.51847/AYOZXtLMrj
%P 1-5
%X This research was performed by a clinical pharmacist to determine the efficacy of dexmedetomidine as an alternative therapy in laparoscopic appendectomy surgery for acute and short-lived analgesic appendicitis and to focus on the consistency of pharmacotherapy and patient safety. A randomized, double-blind, prospective analysis of 2 groups allocated to the fentanyl [GF] and fentanyl dexmedetomidine [GF-D] groups. Propofol, Sevoflurane, Atracurium, and intraoperative fentanyl bolus were administered to the patient, followed by an infusion of maintenance dose of 0.2 μg/kg/h for the two grades. GF patients were given placebo, however, while patients with GF-D received both dexmedetomidine and fentanyl as an infusion (0.5 μg/kg/h).

The requirements for postoperative analgesics and the need for initial postoperative analgesics, consistency of hemodynamic parameters, side effects of nausea and vomiting, and food tolerance have been controlled. GF-D showed lower side effects and food resistance compared to GF: pain score, morphine consumption, nausea, and vomiting (p
%U https://japer.in/article/clinical-pharmacist-intervention-in-appendectomy-dexmedetomidine-as-an-adjunct-therapy-pahuqc3lhnemsfi