TY - JOUR T1 - Association of Interleukin-6 gene polymorphisms with etanercept response in Iraqi patients with rheumatoid arthritis A1 - Dhulfiqar Nidhal Alhilali A1 - Samer Imad Mohammed A1 - Faiq Isho Gorial JF - Journal of Advanced Pharmacy Education and Research JO - J Adv Pharm Educ Res SN - 2249-3379 Y1 - 2025 VL - 15 IS - 4 DO - 10.51847/X9rbtoE5Zc SP - 131 EP - 141 N2 - The present study aimed to examine the role of Interleukin-6 (IL-6) promoter polymorphisms in the response to Etanercept (ETN) treatment in a group (Cohort) of Iraqi RA patients. Ninety active RA patients were chosen and studied at baseline, three to six months post-ETN therapy. The experiment was carried out in the Rheumatology unit at Baghdad Teaching Hospital in Medical City, Baghdad/Iraq. Based on the Disease Activity Score 28-Erythrocyte Sedimentation Rate (DAS28-ESR), the patients were categorized into responders and non-responders. The Results revealed that at baseline, responders were significantly younger than non-responders (P=0.0025). For the responders group; there were a significant enhancement in DAS28-ESR components (P UR - https://japer.in/article/association-of-interleukin-6-gene-polymorphisms-with-etanercept-response-in-iraqi-patients-with-rheu-6c55cmukjgajxpm ER -