%0 Journal Article
%T Association of Interleukin-6 gene polymorphisms with etanercept response in Iraqi patients with rheumatoid arthritis
%A Dhulfiqar Nidhal Alhilali
%A Samer Imad Mohammed
%A Faiq Isho Gorial
%J Journal of Advanced Pharmacy Education and Research
%@ 2249-3379
%D 2025
%V 15
%N 4
%R 10.51847/X9rbtoE5Zc
%P 131-141
%X The present study aimed to examine the role of Interleukin-6 (IL-6) promoter polymorphisms in the response to Etanercept (ETN) treatment in a group (Cohort) of Iraqi RA patients. Ninety active RA patients were chosen and studied at baseline, three to six months post-ETN therapy. The experiment was carried out in the Rheumatology unit at Baghdad Teaching Hospital in Medical City, Baghdad/Iraq. Based on the Disease Activity Score 28-Erythrocyte Sedimentation Rate (DAS28-ESR), the patients were categorized into responders and non-responders. The Results revealed that at baseline, responders were significantly younger than non-responders (P=0.0025). For the responders group; there were a significant enhancement in DAS28-ESR components (P
%U https://japer.in/article/association-of-interleukin-6-gene-polymorphisms-with-etanercept-response-in-iraqi-patients-with-rheu-6c55cmukjgajxpm