TY  - JOUR
T1  - Assessment of wound-healing activity of zinc oxide nanoparticles      ‎
A1  - Vadim Albertovich Melkumyan
A1  - Dzhamilya Abdulvagabovna Kurbanova
A1  - Rusalina Serazhutdinovna Magomedgadzhieva
A1  - Masis Vaagovich Khidiryan
A1  - Stanislav Andreevich Eremin
A1  - Vladimir Sergeevich Stepanenko
A1  - Amina Alhazurovna Dzhankaeva
A1  - Aida Mikhailovna Tanasheva
JF  - Journal of Advanced Pharmacy Education and Research
JO  - J Adv Pharm Educ Res
SN  - 2249-3379
Y1  - 2024
VL  - 14
IS  - 1
DO  - 10.51847/0SQk1Cmx1X
SP  - 73
EP  - 76
N2  - The article presents the results of studying the effect of a complex of zinc oxide nanoparticles on the reparative regeneration of an experimental wound. The analysis of data from planimetric studies (changes in the area of the wound in dynamics, the rate of wound healing, the daily change in the area of the wound) showed a high wound healing activity of the drug, statistically significantly superior to the indicators in the comparison group. Zinc oxide nanoparticles, in addition to regenerating, have an antimicrobial effect and prevent secondary contamination of the wound, which also contributes to full-fledged reparative regeneration. It has been proven that topical application of the drug in animals with experimental conditionally aseptic wounds provides pronounced regenerating and antibacterial effects. This drug can be used to treat skin and soft tissue injuries of various etiologies. The use of the drug for local wound treatment at all stages of complex treatment will reduce the duration of systemic antimicrobial therapy, avoid the development of side effects, significantly reduce the cost of expensive antibacterial drugs, and avoid the formation of resistance of microflora to the systemic antibiotics used.
UR  - https://japer.in/article/assessment-of-wound-healing-activity-of-zinc-oxide-nanoparticles-lrm-ptkumdwnqzncgyu
ER  -