TY  - JOUR
T1  - Advances in understanding antimicrobial resistance and approaches for mitigation
A1  - Mohammed Ibrahim Mobarki
A1  - Abeer Abdulrahman Alkaabi
A1  - Mashael Hussien Alqahtani
A1  - Wed Abdulrahman Alasmri
A1  - Noura Fahad Alkhuwaiter
A1  - Saeed Ali Alasmary
A1  - Dalia Saleh Alghamdi
A1  - Ibrahim Abdulrhman Alsharidah
A1  - Abdulkarim Mohsen Ali Alhakami
A1  - Rayan Mohammed Almohaimeed
A1  - Naif Abdulrahman Alarifi
JF  - Journal of Advanced Pharmacy Education and Research
JO  - J Adv Pharm Educ Res
SN  - 2249-3379
Y1  - 2025
VL  - 15
IS  - 3
DO  - 10.51847/5P5Jo37fEX
SP  - 167
EP  - 177
N2  - Antibiotics have transformed modern medicine, playing a pivotal role in healthcare and saving millions of lives globally. Nevertheless, the rapid rise of antimicrobial resistance (AMR) poses a significant and escalating threat, with the potential to trigger a major public health crisis. This review aims to summarize the microbial and human-driven factors contributing to AMR and highlight the implications of neglecting this challenge. Relevant literature was retrieved from international databases, including PubMed, Scopus, ScienceDirect, and Google Scholar, using combinations of keywords such as “antimicrobial resistance,” “superbug,” “antibiotic stewardship,” “one health,” and “surveillance.” The article examines major drivers of AMR, including inappropriate antibiotic use and the proliferation of resistant bacterial strains, while also discussing strategies to counteract this threat. Proposed measures include implementation of the One Health framework, robust stewardship programs, and the integration of artificial intelligence in drug discovery. Moreover, the potential role of traditional and ethnic medicinal practices in therapeutic interventions has been explored. In summary, this review highlights the urgent need for coordinated, multifaceted action to combat AMR. Future research and innovative strategies are crucial to reducing the burden of resistance and protecting both human and animal health‎.
UR  - https://japer.in/article/advances-in-understanding-antimicrobial-resistance-and-approaches-for-mitigation-mx5uwcgsawphdpq
ER  -