TY  - JOUR
T1  - A stability-indicating method for Levetiracetam in tablets using advanced analytical quality-by-design approach
A1  - Maher Abdulrazzaq Al-hakeem
A1  - Lacramioara Popa
A1  - Cristina Dinu-Pirvu
A1  - Mihaela Violeta Ghica
A1  - Razvan Prisada
JF  - Journal of Advanced Pharmacy Education and Research
JO  - J Adv Pharm Educ Res
SN  - 2249-3379
Y1  - 2021
VL  - 11
IS  - 3
DO  - 10.51847/DwtvdvJkWj
SP  - 126
EP  - 131
N2  - Quality by design (QbD) framework focuses on identifying predetermined specifications where the constraints to the process and the material features of the products are critical. Implementing the QbD concept for the analytical method validation is the modern direction in the pharmaceutical industry This study's basic design involves applying analytical quality by design (AQbD) research phases in the authentication and application of the conventional approaches during the development of a dynamic principal composite design. The influential and predicted positive outcomes of developing the pragmatic AQbD method is an effective method to ensure that the method meets its designated requirements. The study aimed to develop a comprehensive stability-indicating approach of Levetiracetam using AQbD. This study has shown that the QbD approach allows different analytical parameters evaluation and measure. The proposed method for stability indication of Levetiracetam in tablets proved to be fast and straightforward, and the proposed methodology was valid for ruggedness, robustness, accuracy, specificity, and linearity‎.
UR  - https://japer.in/article/a-stability-indicating-method-for-levetiracetam-in-tablets-using-advanced-analytical-quality-by-desi-nkvbejoagilb5sl
ER  -